منابع مشابه
Pseudohypernatremia and pseudohyponatremia: a linear correction.
BACKGROUND Serum sodium is commonly measured by direct potentiometry (DNa), in blood gas panels, or indirect potentiometry (INa), in metabolic panels run on chemistry analyzers. Abnormal values of the serum non-water fraction interfere with INa, with low values causing pseudohypernatremia (INa > DNa) and high values causing pseudohyponatremia (INa < DNa). Previous attempts to derive a linear co...
متن کاملSpurious sodium results (1) – pseudohyponatremia
This is the first of two linked articles that highlight the spurious sodium values that can occur if an indirect ISE technique is used to analyze plasma samples with abnormal protein or lipid concentration. The focus of this first article is spuriously reduced sodium (pseudohyponatremia) due to increased plasma protein or lipid concentration, whilst the subject of the second [1] is spuriously i...
متن کاملRapid measurement of serum water to assess pseudohyponatremia.
Pseudohyponatremia is caused by an increased serum protein or lipid concentration producing a "space-occupying lesion" in serum water. Its presence and magnitude must be assessed in hyponatremic patients with, for example, paraproteinemia or hyperlipemic diabetic coma. In the absence of a direct-reading ion-selective electrode system, a method for measuring the water content of serum is require...
متن کاملPseudohyponatremia: Does It Matter in Current Clinical Practice?
Serum consists of water (93% of serum volume) and nonaqueous components, mainly lipids and proteins (7% of serum volume). Sodium is restricted to serum water. In states of hyperproteinemia or hyperlipidemia, there is an increased mass of the nonaqueous components of serum and a concomitant decrease in the proportion of serum composed of water. Thus, pseudohyponatremia results because the flame ...
متن کاملAsparaginase-Induced Hypertriglyceridemia Presenting as Pseudohyponatremia during Leukemia Treatment
Asparaginase is a chemotherapeutic agent used to induce disease remission in children with acute lymphoblastic leukemia (ALL). We describe the cases of two females with ALL who developed pseudohyponatremia as a presentation of hypertriglyceridemia following asparaginase treatment. Nine similar published cases of asparaginase-induced hypertriglyceridemia and its complications are also discussed....
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2018
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2017.276501